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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12608 | QX-314 chloride | Sodium Channel | |
QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel. | |||
T7638 | NPPB | Chloride channel | |
NPPB is a chloride channel blocker with IC50 of 80 nM . | |||
T15192 | Eact | Chloride channel | |
Eact is a selective and potent TMEM16A activator. It directly activates the TRPV1 channels in sensory nociceptors. Which also produces itch, acute nociception and thermal hypersensitivity. | |||
T8960 | MONNA | Chloride channel | |
MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions. | |||
T7538 | Tetraethylammonium chloride | Potassium Channel | |
Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties. | |||
T10979 | DCPIB | Potassium Channel , Chloride channel | |
DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1... | |||
T1221 | Acetylcholine chloride | ACh chloride,Pilofrin | Calcium Channel , Endogenous Metabolite , AChR |
Acetylcholine Chloride is the chloride salt form of acetylcholine, a synthetic, quaternary amino alcohol with cholinergic properties. Acetylcholine chloride (Pilofrin) mimics the parasympathomimetic effect of the endogen... | |||
T8391 | Cesium chloride | CsCl | Potassium Channel |
Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth. | |||
T0979 | Dequalinium chloride | Dequafungan,Danical,Decabis | Potassium Channel , PKC |
Dequalinium chloride (Decabis) , a topical bacteriostat, is a selective blocker of apamin-sensitive K+ channels. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ... | |||
T13059 | T16Ainh-A01 | Chloride channel | |
T16Ainh-A01 is a potent inhibitor of TMEM16A Chloride channel, inhibiting TMEM16A-mediated chloride currents (IC50 of 1 µM),and functions as a calcium-activated chloride channel (CaCC). | |||
T16346 | NS1652 | Chloride channel | |
NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells. | |||
T23213 | QX-222 chloride | QX 222,Lidocaine N-Methyl Hydrochloride | Sodium Channel |
QX-222 chloride (Lidocaine N-Methyl Hydrochloride) is a sodium channel blocker. | |||
T7191 | Diphenyleneiodonium chloride | DPI | NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel |
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity. | |||
T15233 | Endovion | NS3728 | Chloride channel |
Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker. | |||
T0275 | Meticrane | Fontiliz,Arresten | Chloride channel , Sodium Channel |
Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity. | |||
TN1035 | Irisolidone | IL Receptor , NF-κB , Chloride channel | |
Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM. | |||
T0858 | Flufenamic acid | Arlef,Nichisedan,Achless | Potassium Channel , Calcium Channel , Chloride channel , COX , AMPK , Parasite |
Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. | |||
T2498 | Adjudin | AF-2364 | Chloride channel , Mitochondrial Metabolism |
Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway. | |||
T0693 | Niflumic acid | Nifluril,Forenol,Landruma | Others , Phospholipase , Chloride channel , COX , Monocarboxylate transporter , UGT |
Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis. | |||
T4330 | CaCCinh-A01 | Chloride channel | |
CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM). |